In response to the tragic Pulse Nightclub shooting on June 12, 2016, in Orlando, Florida, Orlando MQG established a quilt drive to collect quilts for the victims and families of those killed. Due to an incredible response from around the world aided by social media and news coverage, we were able to provide quilts to many more including extended family members, first responders, police officers, fire departments, 911 dispatchers, mental health providers, city employees, hospital staff and doctors, and others who were impacted by the shooting. In all, over 1,800 quilts were distributed. This project grew into more than imagined, lasted about 1.5 years, and truly showed the love and compassion from so many worldwide. Due to the scope and visibility of Quilts for Pulse (QFP), Orlando MQG has received requests for information on organizing a large quilt drive. We share our experience and lessons learned in this document and hope your guild or organization can use it as a tool when planning a quilt drive.